Dynamics of Contrast Medium in Experimental Brain Tumors

Experimental Brain Tumors: Current Concepts

The possibility of having experimental models of brain tumors allows for testing therapies applicable to human brain tumors. They can be induced by viruses, chemicals or radiation. Radiation-induced brain tumors have seldom been used, but diverse virus groups have been used to induce brain tumors. Among DNA viruses, both adenoviruses and papovaviruses have been shown to induce brain tumors in a...

Experimental Brain Tumors I. Tumors Produced with Methylcholanthrene*

Efforts to produce intracranial neoplasia by various chemical carcinogens have been attended with scant success prior to the work of Seligman and Shear (2). By intracerebral implantation of pellets of 2o-methylcholanthrene, these workers produced i i gliomas and 2 fibrosarcomas in a series of 2o male mice of the C3H strain. Seligman and Shear reported also successful subcutaneous transplantatio...

Contrast-enhanced MR imaging of malignant brain tumors.

Magnetic resonance (MR) imaging was performed before and serially after intravenous injection of 1 mmol/kg gadolinium-DTPA (Schering) in 17 patients with clinical and histologic diagnosis of malignant cerebral tumors. There was a decrease of 1% in T1 and 10% in T2 in normal white matter and a decrease of 8% in T1 and 14% in T2 in normal gray matter. Contrast enhancement was observed in 16 of th...

brain tumors in elderly

brain tumors in elderly are increasing as the number of people, who comprise the older population, does.about half of the patients with brain tumors appear to be over 60 years of age.in this review article, glioblastoma multiform, as the most common malignant tumor of the central nervous system in elderly is discussed in details of definition, prognosis, diagnosis, treatment and differential di...

Dynamic susceptibility contrast-enhanced perfusion MR Imaging of Brain Tumors